A, The proteasome subunit levels of Rpt4 (19S proteasome subunit) and PSMA6 (20S proteasome subunit) were measured in livers of the chronically treated animals with DIC. B, The proteasome subunit levels of Rpt4 and PSMA6 were measured in kidneys from the acute treatment group. C - control, vehicle treated hearts. D - DIC treated hearts. Values are expressed as mean ± SD (n=4), * P < 0.01, ** p < 0.001.