Table 1. Baseline characteristics of participating cohorts.

Cohort	N	Ndeaths (%)	Follow-up duration (years)*	Age (years)*	rHorvath†	rHannum ‡
1. WHI (White)	995	309 (31%)	15.4 (14.0-16.4)	68 (65-72)	0.67 (p=5.1×10−131)	0.73 (p=8.0×10−167)
2. WHI (Black)	675	176 (26%)	15.4 (13.7-16.5)	62 (57-67)	0.70 (p=1.2×10−100)	0.76 (p=3.0×10−128)
3. WHI (Hispanic)	431	78 (18%)	15.2 (14.1-16.3)	61 (56-67)	0.78 (p=8.9×10−90)	0.79 (p=1.3×10−93)
4. LBC 1921	445	312 (70%)	10.2 (6.2-12.9)	79 (78-79)	0.15 (p=1.5×10−3)	0.13 (p=6.0×10−3)
5. LBC 1936	919	106 (12%)	7.5 (6.9-8.4)	69 (68-70)	0.15 (p=4.9×10−6)	0.16 (p=1.1×10−6)
6. NAS	647	221 (34%)	11.6 (8.6-12.9)	72 (68-77)	0.69 (p=1.3×10−92)	0.76 (p=8.2×10−123)
7. ARIC (Black)	2,768	1,075 (39%)	20.3 (14.3-21.4)	57 (52-62)	0.65 (p<1×10−200)	0.71 (p<1×10−200)
8. FHS	2,614	236 (9%)	6.2 (5.6-6.9)	66 (60-73)	0.84 (p<1×10−200)	0.86 (p<1×10−200)
9. KORA	1,257	42 (3%)	4.4 (4.0-4.8)	61 (54-68)	0.84 (p<1×10−200)	0.88 (p<1×10−200)
10. InCHIANTI	506	91 (18%)	15.0 (14.6-15.5)	67 (57-73)	0.82 (p=3.2×10−124)	0.85 (p=2.1×10−142)
11. Rotterdam	710	32 (5%)	5.6 (5.3-5.8)	58 (54-62)	0.72 (p=1.9×10−114)	0.76 (p=1.3×10−134)
12.Twins UK	805	30 (4%)	8.5 (7.5-8.5)	58 (51-65)	0.87 (p<1×10−200)	0.89 (p<1×10−200)
13. BLSA (white)	317	26 (8%)	5.3 (4.0-6.6)	66 (58-73)	0.85 (p=1.1×10−89)	0.88 (p=7.2×10−104)
Total	13,089	2734 (21%)

The last 3 columns report robust correlation coefficients (biweight midcorrelation) between chronological age and two epigenetic age estimates (Horvath and Hannum).

^*Median (25^th percentile - 75^th percentile)

^†Biweight midcorrelation coefficient of chronological age with epigenetic age using the Horvath method.

^‡Biweight midcorrelation coefficient of chronological age with epigenetic age using the Hannum method.