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. 2016 Sep 5;8(9):1923–1938. doi: 10.18632/aging.101033

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Copyright: © 2016 Jiang et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) Western blot showing YAP down-regulation in the PLKO-YAP group compared to the scrambled group. (B, C) Flow cytometry showing increased VSMC apoptosis in the PLKO-YAP group compared to the scrambled group (repeated 3 times for statistical analysis, *p=0.0013). (D) Western blotting showing YAP down-regulation in the experimental group compared to the control group after cyclic stretching. (E, F) Flow cytometry showing increased VSMC apoptosis compared to the control group after cyclic stretching in vitro (the lower right quadrant (Q4) represents the apoptotic VSMCs, and repeated 3 times for statistical analysis, *p=0.0010).