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. 2016 Oct;2(5):574–582. doi: 10.1016/j.jacep.2016.03.007

Figure 1.

Figure 1

Electrophysiological and Arrhythmia Determinants of Chronic MI Model

(A) Optical mapping of chronic MI hearts. (B) Representative optical action potentials from remote myocardium, IBZ, and infarct zone. (C) Slower CVs at IBZ compared with remote myocardium. (D) Conduction vector angles were more heterogeneous in the infarct zone (MI). (E) Prolonged rise times at the infarct zone and IBZ. (F) Increased dispersion of optical APDs at the infarct zone and IBZ. (C to F) n = 16 for MI hearts, and n = 4 for sham hearts. (G) IBZ CV was slower in PES(+) hearts (n = 8) than in PES(−) hearts (n = 8). *p < 0.05; **p < 0.01; ***p < 0.001. APD = action potential duration; CV = conduction velocity; IBZ = infarct border zone; PES = programmed electrical stimulation.