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Safety study of oncolytic virus M1. (A) Genome of alphavirus M1. (B) Injection interval for the safety study of alphavirus M1. Time is depicted in days. Test, five cynomolgus macaques injected with three rounds of intravenous injections with oncolytic virus M1 (109 pfu in 20 ml); control, five cynomolgus macaques injected with the same volume of vehicle in the same schedule.
