Figure 4.
Hematological examinations of whole blood samples of macaques. Peripheral blood samples from macaques injected with six doses of oncolytic virus M1 (109 pfu/dose) or with vehicle were used to perform complete blood counts (CBC) analysis using an automated counter (Sysmex pocH-100iV). Charts show the numbers of white blood cells (A), platelet cells (D), and hematocrits (B) and the percentages of lymphocytes (C), neutrophilic granulocytes (E), and monocytes (F) for individual macaques at indicated time points. An overview of the individual cynomolgus macaques of the experiment and their animal codes is shown (bottom). Data from different animals are marked with different shapes of symbols; the ID number consists of six digits plus a capital letter. Data from control animals are shown in dashed lines versus solid lines for data from test animals.