FIGURE 7.

Knockdown of NF90 or NF45 promoted reduced HCC cell proliferation. A–C, proliferation of Huh7 cells transfected with siRNAs targeted to NF90 (A) or NF45 (B) and miRNA mimic (C) was analyzed by MTS assay. D, proliferation of Hep3B cells transfected with siRNAs targeted to NF90 or NF45 and miRNA mimic was analyzed by MTS assay. E and F, proliferation of Huh7 cells transfected with siRNAs targeted to NF90 (E) or NF45 (F) with or without miR-7 inhibitor was analyzed by MTS assay. After the indicated days of culture, the assay was performed according to the manufacturer's instructions, and absorbance was measured at 490 nm. Data are expressed as means ± S.D. (n = 3 per group). *, p < 0.05 relative to control by a two-tailed Student's t test.