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. 2016 Aug 16;291(40):21110–21122. doi: 10.1074/jbc.M116.726612

FIGURE 5.

FIGURE 5.

AFM and CD spectroscopy of WT-αS and acetylated-αS fibrils. A, AFM amplitude images depicting fibrillar aggregates of WT-αS (panel 1), NTAc-αS (panel 2), and Endo-αS (panel 3). The scale bar is 250 nm. B, fibril periodicities measured from AFM images show slightly higher values for acetylated-αS compared with WT-αS. C, CD spectroscopy of purified αS fibrils show slightly higher β-sheet content in acetylated-αS fibrils than WT-αS fibrils. All fibrils were prepared in PBS buffer solutions and purified after aggregation to remove monomers.