TABLE 1.

Inhibition of ¹²⁵I-Man-BSA binding to mincle by acylated derivatives of trehalose

Results are reported as means ± S.D. for n = 3–4 separate experiments, each performed in duplicate.

Compound	KI	KI,trehalose/KI, compound
	μm
Trehalose	2200 ± 300
Longer diacylated derivatives
Divalerate	59 ± 2	34 ± 4
Dihexanoate	8.2 ± 0.3	250 ± 30
Longer monoacylated derivatives
Monoheptanoate	137 ± 18	22 ± 2
Monooctanoate	58 ± 8	52 ± 5
Monodecanoate	5.1 ± 0.6	310 ± 30
Monododecanoate	3.1 ± 0.5	530 ± 100
Branched chain derivatives
Monoisobutyrate	1100 ± 100	2.5 ± 0.2
Diisobutyrate	370 ± 40	7.3 ± 0.8