Skip to main content
. Author manuscript; available in PMC: 2017 Sep 26.
Published in final edited form as: Dev Cell. 2016 Sep 26;38(6):635–642. doi: 10.1016/j.devcel.2016.08.015

Figure 3. Mechanisms that mediate long-distance control of growth and differentiation from two opposing signaling domains.

Figure 3

The distal axis (QC, columella, and LRC) regulates both cell division and differentiation gradients by long-distance influence (e.g., RGFs and miR396). The proximal axis (radial cell files) has top-down influence, setting the position of the QC, the upper-most cell of the distal axis, through SCR/SHR and ROW1. These factors influence distal axis division and differentiation through QC factors and potentially other long distance mechanisms to affect columella identity (not shown).