Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 May 24;95(11):1214–1220. doi: 10.1177/0022034516651077

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© International & American Associations for Dental Research 2016

PMC Copyright notice

Figure 3. — Evolutionary conservation of Utp5/WDR43. (A) Conserved WD40 and Utp12 domains predicted by the NCBI Conserved Domain database for Utp5/WDR43 in humans (Homo sapiens) and model organisms, including mice (Mus musculus), frogs (Xenopus tropicalis), zebrafish (Danio rerio), and yeast (Saccharomyces cerevisiae). White boxes indicate the relative lengths of the protein and are drawn to scale with the N-terminus to the left and C-terminus to the right. Yellow boxes indicate WD40 conserved domains (NCBI accession no. cd00200) and are drawn to scale. Cyan boxes indicate Utp12 conserved domains (NCBI accession no. pfam04003) and are drawn to scale. The location of the premature stop codon in fantome mutant zebrafish, which results in craniofacial developmental defects, is indicated in red. (B) Phylogeny tree for Utp5/WDR43 proteins. A ClustalW alignment of the indicated proteins was used to generate a phylogeny tree in the NCBI Genome Browser. This figure is available in color online at http://jdr.sagepub.com.