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. 2015 Oct 29;36(10):1813–1822. doi: 10.1177/0271678X15613955

Figure 5.

Figure 5.

Chronic BHB exposure inhibits astrocytic glycolysis in organotypic hippocampal slices. (a) Expression of the glucose sensor FLII12Pglu700µΔ6 in astrocytes in organotypic hippocampal slices. Bar = 100 µm. (b) Measurement of astroytic glucose consumption rate with 20 µM cytochalasin B in organotypic slices exposed for 3 days to control conditions (gray symbols) or to 2 mM BHB (open symbols). Bars represent the average rates obtained in three separate experiments (8–10 cells per experiment).