Figure 1.

Inflammasome signalling in different cell types involved in brain inflammation and injury. Because of the extensive literature data available, inflammasome signalling in monocytes and macrophages is not discussed in detail only pathways confirmed in the case of microglia. See detailed explanation in the text. Please note that triggers, pathways and downstream events of inflammasome activation were depicted in the figure only if experimental evidence is available for the given cell type.