FIGURE 1.

Ad.mda-7 induces the loss of cell viability in NSCLC cells, but in not non-transformed lung epithelial cells. Cells (1 × 10⁴) were transduced with the indicated MOI (PFU/cell) of either ad.mda-7 or Ad.CMV control virus. After the indicated incubation time, the cells were assayed for cell viability using a WST-1 assay as described under “Experimental Procedures.” A, A549 cells. B, H838 cells. C, H1299 cells. D, HBEC-3KT cells. Data are expressed as mean of the percentage of viability ± S.D. Data are representative of six separate determinations on two separate occasions.