FIGURE 2.

Conserved motifs in Stt7/STN7 kinase family members. A, within the trans-membrane domain, the GXXP motif, which encodes a hinge, is found to be conserved and is shown in a dashed box. The dimerization motif GXXXG is present in the Stt7/STN7 kinase enzyme of all species except Micromonas sp. B, the HRD motif, which is a key signature of kinases, is found to be highly conserved across Stt7/STN7 from all species. However, the DFG motif is replaced by the amino acids DLG, as shown in the figure.