Table 2. Effect of intrathecal ZIP injection on open field test in rats.

	Total walking distance (m)		Average speed (cm/s) ($\overline{\mathrm{\chi }}$ ± SEM)
	Saline	ZIP	Saline	ZIP
Control	18.18±2.55	17.57±3.30	6.06±0.80	5.86±1.10
IBS	9.73±0.70	11.71±2.59	3.25±0.23	3.91±0.86

IBS: irritable bowel syndrome; ZIP: PKMζ inhibitor.