Table 1. Basic biologic and hematologic data for monkeys with and without drusen.
Unit | Total | Drusen + | Drusen - | P-value* | |
---|---|---|---|---|---|
Number | 945 | 317 | 628 | - | |
Sex | %Male | 24.6 | 21.5 | 26.1 | 0.115* |
Weight | kg | 3.38 ± 1.19 | 3.67 ± 1.27 | 3.23 ± 1.13 | < 0.001 |
Age | years | 8.34 ± 5.87 | 10.46 ± 6.35 | 7.28 ± 5.31 | < 0.001 |
WBC | x103/μl | 6.52 ± 2.67 | 6.74 ± 2.76 | 6.42 ± 2.62 | 0.034 |
RBC | x104/μl | 558 ± 64 | 564 ± 66 | 555 ± 62 | 0.090 |
Hemoglobin | g/dl | 11.0 ± 1.0 | 11.1 ± 1.1 | 11.0 ± 1.0 | 0.102 |
Platelet | x105/μl | 3.21 ± 0.90 | 3.30 ± 0.96 | 3.17 ± 0.87 | 0.051 |
Protein | g/dl | 7.05 ± 0.51 | 7.08 ± 0.53 | 7.03 ± 0.50 | 0.045 |
Albumin | g/dl | 4.11 ± 0.34 | 4.06 ± 0.33 | 4.14 ± 0.35 | < 0.001 |
BUN | mg/dl | 17.5 ± 5.4 | 17.1 ± 5.8 | 17.7 ± 5.2 | 0.016 |
Glucose | mg/dl | 45.5 ± 20.0 | 47.9 ± 25.0 | 44.3 ± 16.7 | 0.054 |
Cholesterol | mg/dl | 111 ± 30 | 115 ± 30 | 108 ± 30 | < 0.001 |
Tryglyceride | mg/dl | 45.4 ± 45.3 | 50.0 ± 51.5 | 43.2 ± 41.7 | 0.034 |
Phosphate | mg/dl | 4.52 ± 1.47 | 4.31 ± 1.31 | 4.62 ± 1.54 | 0.002 |
Calcium | mg/dl | 9.21 ± 0.56 | 9.19 ± 0.70 | 9.22 ± 0.48 | 0.864 |
GOT | IU/l | 53.7 ± 19.0 | 53.7 ± 18.2 | 53.7 ± 19. 5 | 0.990 |
GPT | IU/l | 74.6 ± 57.7 | 78.1 ± 62.0 | 72. 7 ± 55.4 | 0.245 |
CRP | mg/dl | 0.111 ± 0.219 | 0.127 ± 0.239 | 0.103 ± 0.208 | 0.017 |
*Except for sex, which was evaluated using the chi-squared test, the Mann–Whitney U-test was used to test for differences between monkeys with and without drusen. Data represents the mean ± one standard deviation. WBC, white blood cells; RBC, red blood cells; BUN, blood urea nitrogen; GOT, glutamate oxaloactetate transaminase; GPT, guanine phosphoribosyl transferase; CRP, C-reactive protein.