Table 4. Laboratory findings of 48 case-patients with severe fever with thrombocytopenia syndrome at admission grouped according to outcome in Japan.
| Total (n = 48) | Non-fatal (n = 33) | Fatal (n = 15) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Normal range | n | Median | IQR | n | Median | IQR | n | Median | IQR | p-value | ||
| Hb | (g/dL) | M: 13.7–16.8F: 11.6–14.8 | 48 | 14.0 | 12.0–14.9 | 33 | 14.1 | 12.0–14.9 | 15 | 13.2 | 12.2–14.3 | 0.34 |
| WBC | (/μL) | 3300–8600 | 48 | 1725 | 1170–2668 | 33 | 1770 | 1400–2570 | 15 | 1290 | 965–2750 | 0.22 |
| Platelet | (×104/μL) | 15.8–34.8 | 48 | 6.3 | 4.3–9.4 | 33 | 7.1 | 5.8–9.9 | 15 | 4.2 | 2.4–6.5 | 0.004 |
| AST | (IU/L) | 13–30 | 48 | 125 | 80–252 | 33 | 104 | 61–186 | 15 | 243 | 108–439 | 0.02 |
| ALT | (IU/L) | M: 10–42F: 7–23 | 48 | 55 | 39–108 | 33 | 53 | 31–97 | 15 | 61 | 48–180 | 0.13 |
| LDH | (IU/L) | 124–222 | 47 | 431 | 351–908 | 32 | 406 | 328–659 | 15 | 831 | 402–1064 | 0.06 |
| Albumin | (g/dL) | 4.1–5.1 | 48 | 3.4 | 3.1–3.8 | 33 | 3.7 | 3.3–3.9 | 15 | 3.0 | 2.8–3.4 | 0.02 |
| BUN | (mg/dL) | 8–20 | 48 | 22 | 17–29 | 33 | 21 | 16–25 | 15 | 25.6 | 19.7–36.1 | 0.06 |
| Cr | (mg/dL) | M: 0.65–1.07F: 0.46–0.79 | 48 | 0.93 | 0.70–1.13 | 33 | 0.82 | 0.70–1.07 | 15 | 1.12 | 0.98–1.38 | 0.01 |
| CRP | (mg/dL) | 0.00–0.14 | 47 | 0.16 | 0.05–0.50 | 32 | 0.14 | 0.05–0.36 | 15 | 0.27 | 0.04–0.78 | 0.35 |
Note: Abbreviations. n, number; IQR, interquartile range; M, male; F, female; Hb, hemoglobin; WBC, white blood cell; AST, aspartate aminotransferase; ALT, alanine aminotransferase; LDH, lactate dehydrogenase; BUN, blood urea nitrogen; Cr, creatinine; CRP, C-reactive protein