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. 2016 Oct 18;11:5415–5427. doi: 10.2147/IJN.S111950

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© 2016 Chen et al. This work is published and licensed by Dove Medical Press Limited

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(A) In vivo noninvasive images of time-dependent whole body imaging of MDA-MB-231 tumor-bearing mice after injection of HTM and PHTM; (B) ex vivo optical images of tumors and organs; and (C) the fluorescence intensity in the tumor region of MDA-MB-231 tumor-bearing mice sacrificed at 48 h (n=3).

Note: *P<0.05.

Abbreviations: h, hours; HA, hyaluronic acid; HTM, HA-PHis/TPGS2k mixed micelles; PHis, poly(L-histidine); pep-TPGS2k, Her2 peptide-modified TPGS2k; PHTM, HA-PHis/pep-TPGS2k mixed micelles; TPGS2k, d-α-tocopheryl polyethylene glycol 2000.