Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
| assay | 6jc48-1 |
|---|---|
| Purity (LC-MS-MS) | >95% |
| Solubility (laser nephelometry) | >50 μg/ml (n=3) |
| Liver microsome stability (human; 1h 37 oC) | Half-life >60 min; |
| clearance <23 μl/min/mg | |
| Plasma protein binding (human, TransilTM) | 89%±3 |
| P450 enzyme inhibition (IC50 fluorescence) | |
| CYP3A4/ DBF | >10 μM |
| CYP3A4/ BFC | 1.3 μM |
| CYP2D6/ AMMC | >10 μM |
| CYP2C19/CEC | >10 μM |
