Table 1.
Studies of acquired antibody to VAR2CSA DBL domains in African women, indicating the relationship between antibody levels and maternal parity. Timing of sample collection during pregnancy or delivery is indicated.
| DBL domain | Significant increase with parity | No difference with parity |
|---|---|---|
| DBL1 | Oleinikov [42] (Delivery) | Tuikue Ndam [39] (Enrollmenta & Delivery) |
| DBL1–DBL2 | Tuikue Ndam [10] (Enrollmenta & Delivery) |
|
| ID1–ID2a | Babakhanyanb [40] | |
| DBL3 | Oleinikov [42] (Delivery) Tuikue Ndam [10] (Enrollmenta & Delivery) |
Brolin [33] (3rd trimester) |
| DBL4 | Tuikue Ndam [10] (Delivery) | Oleinikov [42] (Delivery) Tuikue Ndam [10] (Enrollmenta) |
| DBL5 | Brolin [33] (3rd trimester) Gangnard [44] (During pregnancy)c Gnidehou [43] (2nd and 3rd trimester) Salanti [14] (Delivery) Tuikue Ndam [39] (Enrollmenta & Delivery) Tuikue Ndam [10] (Enrollmenta) |
Oleinikov [42] (Delivery) Tuikue Ndam [10] (Delivery) |
| DBL6 | Oleinikov [42] (Delivery) Tuikue Ndam [39] (Enrollmenta & Delivery) |
Brolin [33] (3rd trimester) Tuikue Ndam [10] (Enrollmenta & Delivery) |
a
Samples collected at enrollment at any time during the first 6 months of gestation.
b
Samples collected during the 1st, 2nd and 3rd trimester.
c
Samples collected during pregnancy, but timing is not specified.