Serum cytokines in melanoma patients treated with radiation and ipilimumab analyzed by Luminex (A) Heat map showing the expression of 63 cytokines in patients with progressive disease (PD) or complete response/partial response (CR/PR) following treatment, at baseline and 2nd and 4th doses of ipilimumab (visit 2 and 3, resp.). (B) Serum levels of (clockwise) MIP1α, IP-10, MIG and MIP1β. PD=Progressive Disease, CR/PR=Complete Response/Partial Response.