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. 2016 Oct 24;11(10):e0165034. doi: 10.1371/journal.pone.0165034

Table 3. MeanRR, SDNN, RMSSD and heart rate during rest in sitting and supine position.

Placebo Caffeine
Pre Post Pre Post Δ p-value
MeanRR (supine) [ms]
    AB 1076 [823; 1273] 1240 [895; 1353]* 1108 [881; 1436] 1176 [1004; 1477] 0.53
    P 922 [770; 1153] 1049 [910; 1262]* 974 [781; 1262] 1078 [857; 1449]* 0.77
    T 1158 [908; 1326] 1247 [1036; 1415]* 1229 [829; 1355] 1347 [975; 1647]* 0.40
MeanRR (sitting) [ms]
    AB 1088 [761; 1276] 1194 [786; 1377]* 991 [803; 1401] 1130 [892; 1358] 0.94
    P 864 [707; 1111] 906 [756; 1180]* 946 [736; 1060] 995 [758; 1286]* 0.21
    T 1130 [789; 1307] 1142 [900; 1223] 1139 [757; 1213] 1217 [867; 1633]* 0.50
SDNN (supine) [ms]
    AB 44 [12; 82] 48 [11; 111] 34 [18; 94] 57 [18; 98]* 0.91
    P 28 [10; 79] 36 [12; 107] 31 [13; 60] 39 [12; 69] 0.09
    T 31 [11; 91] 38 [25; 87] 38 [8; 66] 42 [20; 65] 0.50
SDNN (sitting) [ms]
    AB 49 [14; 89] 50 [17; 95] 39 [15; 99] 53 [19; 107] 0.75
    P 29 [13; 95] 42 [14; 95]* 33 [17; 61] 33 [12; 74] 0.09
    T 30 [6; 42] 35 [21; 66] 26 [7; 62] 33 [22; 66] 0.61
RMSSD (supine) [ms]
    AB 50 [7; 126] 58 [9; 158]* 40 [21; 156] 71 [20; 130] 0.58
    P 34 [7; 100] 43 [13; 136]* 35 [9; 70] 41 [9; 102] 0.11
    T 41 [14; 130] 55 [33; 126] 52 [8; 99] 50 [27; 108] 0.74
RMSSD (sitting) [ms]
    AB 53 [10; 138] 65 [10; 147] 30 [15; 161] 54 [21; 140]* 1.0
    P 32 [9; 100] 38 [9; 107] 32 [11; 56] 35 [7; 70] 0.44
    T 32 [7; 51] 40 [26; 84] 29 [7; 82] 43 [23; 103] 0.73
HR (supine) [1/min]
    AB 56 [47; 73] 49 [45; 67]* 54 [42; 68] 52 [41; 61] 0.24
    P 65 [52; 78] 57 [48; 66]* 62 [48; 77] 56 [41; 71]* 0.68
    T 52 [45; 66] 48 [42; 58]* 49 [44; 72] 45 [36; 62]* 0.40
HR (sitting) [1/min]
    AB 56 [47; 79] 51 [44; 76]* 60 [43; 75] 54 [45; 68] 0.94
    P 70 [54; 85] 66 [51; 79]* 64 [57; 82] 61 [47; 79]* 0.52
    T 53 [46; 76] 53 [49; 67] 53 [50; 79] 49 [37; 69] 0.74

AB = able-bodied participants; P = paraplegic participants, T = tetraplegic participants; MeanRR, = mean of the RR interval; SDNN = standard deviation of all normal RR intervals; RMSSD = the squared root of the mean squared differences of successive RRI intervals; HR = heart rate

* significant change from pre to post ingestion (p < 0.05)

Δ p-value = p-value comparing the difference between pre and post measurement of the placebo trial with the difference from the caffeine trials