Table 1. Genes regulated by IL-1β.

Gene symbols	Regulation (Up or Down)	Fold change	Gene tytles
TNFRSF9	Up	3.5	tumor necrosis factor receptor superfamily, member 9
C3	Up	2.8	complement component 3
IL6	Up	2.4	interleulin-6
NFKBIA	Up	1.8	I-kappa-B-alpha
CLDN1	Up	1.6	claudin-1
NFE2L3	Up	1.6	nuclear factor 3
RNU4-2	Down	0.51	RNA U4 small nuclear 2

DNA microarray experiments were repeated three times. Gene expression levels were compared between IL-1β-unstimulated and stimulated cells. Fold change was calculated as the ratio of IL-1β-stimulated signal to unstimulated signal. Significantly upregulated or downregulated genes (≥1.5-fold or ≤1/1.5-fold, p<0.05) are listed.