Skip to main content
. 2016 Sep 13;291(43):22583–22593. doi: 10.1074/jbc.M116.742304

FIGURE 5.

FIGURE 5.

Promoter mutational analysis shows relative luciferase activity of wild type (wt) and mutant (mut) promoters of Bdnf exon IX. COX6b served as the positive control. Mutating the NRF-2 binding site in COX6b, and sites I and II in Bdnf resulted in a significant decrease in luciferase activity as compared with the wild type controls (down to 40% for COX6b mutant and to 62.44 and 52% for Bdnf sites I and II mutants, respectively). n = 3 for each construct. **, p < 0.01; *, p < 0.05 as compared with the respective wild type controls.