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. 2016 Aug 30;291(43):22741–22756. doi: 10.1074/jbc.M116.747568

FIGURE 8.

FIGURE 8.

SQV and DRV inhibitor binding within the catalytic pocket of HIV-1 PR. Left, overlaid comparison of overall conformation of SQV, with corresponding electron density maps as found in subtype B, E35D, and PR5. Right, overlaid comparison of overall conformation of DRV, with corresponding electron density maps as found in subtype B, E35D, and PR5. SQV and DRV in subtype B construct are obtained from PDB codes 3TKG (49) and 3BVB (54).