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. 2016 Aug 30;291(43):22741–22756. doi: 10.1074/jbc.M116.747568

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© 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 9. — Bar graphs of the prevalence of E35D (A) and R57K (B) as natural polymorphisms in HIV-1 PR subtypes and CRFs are shown, and data are not shown when the total number of isolates is smaller than 5. C, population percentage change (δP%) of the E35D and R57K natural polymorphisms under PI treatments, where δP% = (P(in PI-treated patients) − P(in drug-naive patients))/(P(in drug-naive patients)) × 100. The insets show the enlarged bar graphs of subtype F. Data were not included for TPV-, APV-, lopinavir-, and DRV-treated subtype F patients due to the limited number of DNA sequences.