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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Radiat Res. 2016 Sep 19;186(4):385–395. doi: 10.1667/RR14463.1

Figure 2. 2-AAPA induces cytotoxicity that is reversible with NAC as well as inhibiting both GR and TR activity.

Figure 2

MDA-MB-231 (black bars) and SUM159 cells (gray bars) were treated with 15 mM NAC for 24 hours and/or 20 µM – 100 µM 2-AAPA for 3 hours. Cells were harvested and then analyzed for GR activity (A), TR activity (B), or clonogenic survival (C). Errors ± 1 SEM of at least 3 separate experiments. * p<0.05 vs. control. α p<0.001 vs. treatment without NAC.