Figure 4. Effect of β-Lap on BLM-induced lung fibrosis. Lung tissues from bleomycin (2 mg/kg) and/or β-Lap (20 mg/kg)–treated mice were immunohistochemically stained with anti-mouse TGF-β1 (A) and α-SMA (B) antibodies, as described in the Materials and Methods section. β-Lap: β-lapachone; BLM: bleomycin; TGF-β1: transforming growth factor β1; α-SMA: α-smooth muscle actin.
