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. 2016 May 17;7(22):31602–31622. doi: 10.18632/oncotarget.9395

Figure 7. Involvement of ROCK in growth of T4-2 cells co-cultured with fibroblasts in IrECM.

Figure 7

A. In the presence (left panel) or absence (right panel) of cultured human lung fibroblats, YFP-T4-2 cells were plated in unsupplemented DMEM/F12, and then IrECM was dropped into the co-culture system. C. YFP-T4-2 cells co-cultured with human lung fibroblasts were treated with ROCK inhibitor (Y-26732, 30 and 100 μM) or EGFR inhibitor (AG1478, 0.1 μM). The brightness of YFP in T4-2 cells per well was measured. Values represent means ± SE of six experiments. **P < 0.01 compared with vehicle control group (Dunnett). ## P < 0.01 compared with vehicle control group (Student's t).