Table 1. RT-PCR analysis of liver gene expression following PHx in the Gal1-KO compared to WT mice.

Genes			Hours post-PHx			Il6-induced	Inflam-mation	Lipid meta-bolism	Other
Gene symbol	Gene ID NCBI	Alternative name	2	6	24	2 h #
Acly	104112	Atpcl	−	down	NC			V
Atf3	11910	Lrf1	down	NC	NC				V
Ccl3	20302	Mip1a	−	NC	down		V
Ccna1	12427	Cyclin A	−	−	NC				V
Ccr1	12768	Rantes-R	−	−	down		V
Cd14	12475		down	down	down	V	V
Cd36	12491	Fat	−	−	NC*		V	V
Cidec	14311	Fsp27	−	NC	down			V
Crem	12916	Icer	NC	NC	−				V
Egr1	13653	Ngfi-A	NC	NC	NC	V	V
Fabp4	11770	Afabp	−	down	down			V
Flt1	14254	Vegfr1	−	−	down*				V
Fos	14281	c-Fos	NC	NC	−	V			V
Gadd45a	13197	Ddit1	NC	NC	NC	V			V
Hgf	15234	Sf	−	−	NC*				V
Hif1a	15251	Mop1	−	−	NC*				V
Igfbp1	16006	Ibp1	NC	NC	−	V			V
Il6	16193	Ifnb2	down	NC	NC		V
Jun	16476	Ap-1c	down	NC	NC	V			V
Kdr	16542	Vegfr2, Flk1	−	−	NC*				V
Lgals1	16852	Galectin-1	ND	ND	ND*		V
Lgals3	16854	Galectin-3	−	NC	NC		V
Lta	16992	Lymphotoxin α	ND	ND	-		V
Ltb	16994	Lymphotoxin β	NC	NC	NC		V
Ltbr	17000	Lymphotoxin β receptor	down	down	NC		V	V
Map2k4	26398	Jnkk1, Mek4	Up	NC	NC	V			V
Myc	17869	c-Myc	Up	Up	NC	V			V
Plau	18792	u-PA	NC	Up	−	V			V
Plin4	57435	S3-12	−	down	down			V
Ppara	19013	Ppar, Nr1c1	NC	NC	NC			V
Saa1	20208	Saa-1	−	NC	NC		V
Socs3	12702	Cis3	−	NC	NC		V
Tgfb1	21803	Tgf-beta1	NC	NC	down*				V
Thpo	21832	Thrombopoietin	down	NC	−	V			V
Tnf	21926	Tnf-alpha	NC	NC	down		V
Tnfaip3	21929	A20	NC	Up	down	V	V
Tnfsf14	50930	Light, Hveml	NC	NC	NC		V
Zfp36	22695	Tristetraprolin	NC	Up	Up	V	V

NC - not changed (comparable expression in WT and Gal1-KO post-PHx livers)

ND - not detected; Up – up-regulated; down – down-regulated; − not tested

^*tested by semi-qRT-PCR; others were tested by qRT-PCR

“Up” or “down” at least two-fold in Gal1-KO compared to WT post-PHx liver is shown in bold

^#genes whose induction at 2 h post-PHx was IL6-dependent [Li, 2001 #1370].