Figure 7. MiR-708 increases the sensitivity of tumor cells to Dox treatment in vivo.

A. Tumor size was compared between the four treatment groups and was calculated as πab/4 (a and b are the x and y diameters). MiR-708-overexpressing tumors showed greater sensitivity to Dox treatment than control mice. The results are expressed as the mean ± SD. Each point represents an average of seven mice. B. Tumor weights are plotted according to treatment groups. *P < 0.05 and ** P < 0.01.