Table 3. Results of meta-analysis of LMR and characteristics of six types of cancer.
| Characteristics | Studies | Patients | OR (95% CI) | P value | Heterogeneity | |
|---|---|---|---|---|---|---|
| I2 (%) | P value | |||||
| Urothelial carcinoma | ||||||
| pT stage | 3 | 374 | 0.86 (0.51–1.47) | 0.588 | 0 | 0.414 |
| Tumor grade | 3 | 374 | 1.07 (0.62–1.85) | 0.805 | 0 | 0.825 |
| Esophageal cancer | ||||||
| Tumor length | 2 | 566 | 0.66 (0.44–0.98) | 0.041 | 0 | 0.466 |
| pT stage | 2 | 566 | 0.59 (0.40–0.86) | 0.007 | 0 | 0.808 |
| Lymph node status | 2 | 566 | 0.59 (0.41–0.84) | 0.004 | 0 | 0.630 |
| Gastric cancer | ||||||
| Tumor grade | 2 | 815 | 0.88 (0.64–1.22) | 0.444 | 17.1 | 0.272 |
| TNM stage | 2 | 815 | 0.52 (0.39–0.70) | < 0.001 | 92.2 | < 0.001 |
| Renal cell carcinoma | ||||||
| Fuhrman grade | 2 | 1119 | 0.52 (0.39–0.69) | < 0.001 | 0 | 0.576 |
| Tumor necrosis | 2 | 1119 | 0.57 (0.43–0.75) | < 0.001 | 45.2 | 0.177 |
| Lung cancer | ||||||
| ECOG performance status | 2 | 558 | 0.59 (0.39–0.90) | 0.013 | 47.1 | 0.169 |
| Diffuse large B-cell lymphoma | ||||||
| Ann Arbor stage | 6 | 2869 | 0.42 (0.36–0.49) | < 0.001 | 29.3 | 0.194 |
| IPI score | 4 | 1907 | 0.38 (0.31–0.47) | < 0.001 | 0 | 0.727 |
| ECOG performance status | 5 | 2701 | 0.39 (0.31–0.48) | < 0.001 | 74.3 | 0.001 |
| Extranodal sites of disease | 6 | 2869 | 0.58 (0.48–0.69) | < 0.001 | 61.6 | 0.011 |
| Serum LDH level | 6 | 2869 | 0.27 (0.23–0.32) | < 0.001 | 68.9 | 0.002 |
| B symptom | 2 | 962 | 0.38 (0.25–0.58) | < 0.001 | 0 | 0.364 |
| Hodgkin's lymphoma | ||||||
| Ann Arbor stage | 4 | 1188 | 0.42 (0.33–0.53) | < 0.001 | 78.6 | 0.003 |
| Stage | 3 | 1085 | 0.40 (0.31–0.52) | < 0.001 | 81.5 | 0.005 |
| IPS | 2 | 609 | 0.26 (0.16–0.42) | < 0.001 | 0 | 0.723 |
| WBC count | 4 | 1188 | 0.67 (0.46–0.99) | 0.047 | 0 | 0.686 |
| Albumin | 4 | 1188 | 0.47 (0.36–0.60) | < 0.001 | 68 | 0.025 |
| Hemoglobin | 4 | 1188 | 0.41 (0.30–0.56) | < 0.001 | 57.8 | 0.068 |
LMR, lymphocyte to monocyte ratio; OR, odds ratio; CI, confidence interval; ECOG, eastern cooperative oncology group; IPI, international prognostic index; LDH, lactate dehydrogenase; IPS, international prognostic score.