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. 2016 Mar 3;7(22):31980–31992. doi: 10.18632/oncotarget.7881

Figure 2. Irreversibility of SAR405838 on CD34+ progenitors.

Figure 2

A, B, C, D, E, F. Cells were treated with various doses of MI-219 or SAR405838 for 3 days (A, B, C) or 5 days (D, E, F), washed and seeded in methylcellulose (A, B, D, E) or in fibrin clot (C, F) to assay the number of BFU-E, CFU-GM and CFU-MK progenitors. Results are presented as percentages compared to control. The results represent the mean of 2 experiments made in triplicate. * represents statistical significance (* P<0.05; **P<0.01; ***P<0.001).