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. 2016 Apr 7;7(22):32375–32393. doi: 10.18632/oncotarget.8632

Figure 7. G6PD is up-regulated in human resected HCCs and correlates with NQO1 and KRT-19 mRNA levels.

Figure 7

A. Average levels of G6PD expression in human resected HCCs (n=59) and their peritumoural cirrhotic liver (Liver Cirrhosis, LC; n=59). G6PD mRNA expression is calculated as fold change difference compared to LC. β-actin was used as endogenous control; *P <0.05. B. G6PD mRNA levels correlate with high-grade (Edmonson III-IV), (P = 0.04). C. Scatter-plot graphic showing a positive correlation between NQO1 and G6PD mRNA levels in human resected HCCs; D. Scatter-plot graphic showing an positive correlation between KRT-19 and G6PD mRNA levels in the same human HCCs.