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. 2016 Apr 11;7(22):32493–32503. doi: 10.18632/oncotarget.8679

Figure 1. Cells from hepatocarcinoma express MDR transporters and SLAMF3 inhibited specifically MRP-1 expression.

Figure 1

Total mRNA from human HCC Huh-7 cells WT, free plasmid transfected cells (Mock) and SLAMF3 overexpressing cells transfected with SLAMF3 plasmid were extracted and MRP-1 a. ABCG2 b. and MDR c. genes expression was quantified by qRT-PCR. The results are presented as the mean ± SD from three independent experiments (n = 3; **p<0.01). d. Proteins extracted from mock and SLAMF3+ were analyzed by Western blot for MRP-1 expression (190 kDa). The SLAMF3 (90-110 kDa) expression level was shown for each condition mock and SLAMF3+ cells. One representative result from three independent experiments is shown.