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. 2016 Apr 16;7(22):32876–32892. doi: 10.18632/oncotarget.8765

Figure 6. FSS-induced EMT in Hep-2 cells depended on FAK signaling cascade.

Figure 6

A. The F-actin changing by FSS in Hep-2 cells depended on the assembly of cytoskeletal proteins, Talin, Vinculin, Zyxin and α-actinin. B. FSS regulated the expression change of FAK. C. The Hep-2 cells with EMT enhance their migration ability depended on increased expression level of Rho-family GTPases (RhoA, Rac1 and Cdc42). The expression levels were quantified and statistically analyzed by image analysis of Western blot bands. *, means statistically significant difference with P<0.05.