Figure 6. Combination treatment and inhibition of tumor growth in BGC-823 xenograft nude mice.
A. The animal weight and RTV were examined in vivo. B. Representative photographs of tumors respectively, in each group at the end of experiment. C. The cleaved PARP and p-ERK1/2 were checked by western blot analysis in DT-13-TPT combination-treated group. D-E. Tumor tissues from BGC-823-xenografted nude mice after DT-13-TPT combination treatment were analyzed by TUNEL assays, and immunohistochemistry staining of cleaved caspase-3, p-ERK, Cav-1, EGFR and NM IIA. Statistical analysis was performed using one-way ANOVA followed by Bonferroni's Multiple Comparison Test, *P< 0.05; **P< 0.01; ***P< 0.001.