Table 3. Top differentially regulated genes between mammary tumors and DTC tumorsa.
| Gene Symbol | log2 Fold Change mammary vs. DTC tumor | P Value |
|---|---|---|
| Tfap2b | 4.00 | 0.00004 |
| Abpb | 2.66 | 0.02277 |
| Mfi2 | 1.72 | 0.01500 |
| Arhgef6 | 1.62 | 0.03335 |
| Igfals | 1.54 | 0.01500 |
| S100b | 1.27 | 0.03968 |
| Crabp2 | 1.27 | 0.02177 |
| Nes | 1.26 | 0.01500 |
| Cpeb2 | 1.18 | 0.04957 |
| C630004H02Rik | 1.07 | 0.02490 |
| Cgrrf1 | 1.06 | 0.03335 |
| Clybl | 1.04 | 0.04957 |
| Slc44a3 | 1.02 | 0.03936 |
| Vegfa | −1.03 | 0.04872 |
| Itga9 | −1.21 | 0.03968 |
| Il2rg | −1.24 | 0.02322 |
| Ppp1r9a | −1.36 | 0.01500 |
| Pfkfb3 | −1.42 | 0.01808 |
| Bnip3 | −1.87 | 0.03936 |
| Eps8 | −1.95 | 0.01808 |
| Adm | −2.00 | 0.01808 |
| Ndrg1 | −2.28 | 0.01500 |
| Tspan8 | −2.30 | 0.04836 |
| 2610528A11Rik | −2.51 | 0.04746 |
| Dcpp1 | −3.93 | 0.01500 |
| Dcpp2 | −4.59 | 0.02490 |
a)
RNA from DTC tumors and mammary tumors where used to hybridize Affymetrix chips. Top differentially expressed genes were calculated using cut-off of 0.05 P value with the Bonferroni correction method. The table lists differentially expressed genes (gene symbols), their magnitude expressed as fold change of mammary vs. DTC tumor expression level (Log2 Fold Change) and the False Discovery Rate (FDR) P-value score.