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. 2016 Apr 21;7(22):33179–33191. doi: 10.18632/oncotarget.8891

Figure 2. Clonogenic survival assays in SKOV3, CP20 and ES2 cells.

Figure 2

Increased SKOV3 proliferation was observed after treatment with 10 uM (1.6 fold, p<0.001) and 20 uM (1.9 fold, p=0.018) 5-HT. DOI increased SKOV3 survival at 10 uM (1.4 fold, p=0.014) and 20 uM (1.4 fold, p=0.14) doses. CP20 cell proliferation increased with 20 uM 5-HT (1.16 fold, p<0.001) and 20 uM DOI (1.17 fold, p<0.001) but was not changed by 10 uM 5-HT (p=0.79) or 10uM DOI (p=0.18). ES2 cell proliferation was increased by 10 uM 5-HT (1.17 fold, p<0.01) and 20 uM 5-HT (1.20 fold, p<0.01). ES2 cell proliferation was not changed by 10 uM DOI (p=0.43) and 20 uM (p=0.13). Results represented as the mean +/− SEM.