Table 1. Uni- and multivariate analyses of pathophysiological parameters and BH-3 only gene expression in association with disease-free survival from Dataset-1.

Variable	Univariate (Cox)			Multivariate (Cox) - Stepwise
n=175	HR	95% CI	p	HR	95% CI	P
Age>50	1.10	0.81 to 1.67	0.670		ns
Tumor size >2 cm	1.16	0.76 to 1.78	0.486		ns
Mitotic grade	2.05	1.32 to 3.17	0.002	2.11	1.36 to 3.27	0.001
Vascular invasion	1.50	0.97 to 2.33	0.068		ns
ER status	0.72	0.47 to 1.11	0.140		ns
PR status	0.66	0.43 to 1.0	0.050		ns
HER2 status	1.14	0.67 to 1.97	0.628		ns
Overall grade	1.95	1.18 to 3.21	0.009		ns
Menopausal status	0.87	0.57 to 1.33	0.527		ns
Bad	0.73	0.48 to 1.11	0.145		ns
Bid	1.75	1.14 to 2.68	0.011		ns
Bik	1.79	1.09 to 2.92	0.021	1.89	1.16 to 3.09	0.011
Noxa	0.73	0.47 to 1.11	0.143		ns
Puma	1.35	0.89 to 2.10	0.166		ns

ns= non significant