Table 3. Uni- and multivariate analyses of Bik and anti-apoptotic Bcl-2 family members gene expression in association with disease-free survival from Dataset-1.

Variable	Univariate (Cox)			Multivariate (Cox) - Stepwise
n=175	HR	95% CI	p	HR	95% CI	p
Mitotic grade	2.05	1.32 to 3.17	0.002	1.83	1.16 to 2.89	0.010
Bik	1.79	1.09 to 2.92	0.021	1.66	1.01 to 2.74	0.047
Bcl-2	0.40	0.26 to 0.62	<0.0001	0.47	0.30 to 0.73	0.031
Bcl-xL	0.65	0.43 to 0.99	0.045	0.63	0.41 to 0.96	0.031
Mcl-1	0.55	0.34 to 0.87	0.010	0.48	0.30 to 0.77	0.003
Bcl-w	1.24	0.75 to 2.04	0.399		ns

ns=non significant