Table 2. Association of PDGF-B rs1800818 polymorphism with severe fever with thrombocytopenia syndrome.
Genotypes | Patients (n = 1020) | Controls (n = 1353) | Model | OR (95% CI)a | P valuea |
---|---|---|---|---|---|
AA | 799 (83.1) | 1115 (82.4) | Reference | ||
AG | 151 (15.7) | 135 (10.0) | Codominant | 1.57 (1.20-2.05) | < 0.001 |
GG | 11 (1.1) | 3 (0.2) | 6.18 (1.59-23.98) | ||
AG + GG | 162 (16.9) | 138 (10.2) | Dominant | 1.66 (1.28-2.16) | < 0.001 |
Recessive | 5.80 (1.50-22.48) | 0.005 | |||
Overdominant | 1.55 (1.18-2.03) | 0.001 | |||
Log-additive | 1.68 (1.31-2.15) | < 0.001 |
Abbreviations: OR, odds ratio; CI, confidence interval;
The ORs and P values were adjusted for age, sex, and underlying medical conditions.