Table 9. Progression Free Survival profile by Log-Rank analysis.
Factors | PFS | ||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NSCLC | ESOC | CRC | H&NC | GC | |||||||||||||||||
PFS (day) | 95% CI | p | PFS (day) | 95% CI | p | PFS (day) | 95% CI | p | PFS (day) | 95% CI | p | PFS (day) | 95% CI | p | |||||||
General PFS | 173 | 33.1 | 312.9 | 196 | 0 | 411 | 217 | 181 | 253 | 198 | 102 | 294 | 142 | 18.8 | 265 | ||||||
Sex | Male | 173 | 112 | 233.9 | 0.23 | 196 | 0 | 411 | NA | 210 | 170 | 250 | 0.76 | 302 | 0 | 635 | 0.04 | . | . | . | 0.03 |
Female | 89 | 76.2 | 101.8 | NA | NA | NA | 225 | 114 | 336 | 127 | 31.4 | 223 | 127 | 42.4 | 212 | ||||||
Age | <60y | 104 | 21.9 | 186.1 | 0.04 | 196 | 0 | 408 | 0.56 | 210 | 78.2 | 342 | 0.59 | 198 | 0 | 415 | 0.48 | 253 | 0 | 517 | 0.62 |
≥60y | 521 | 225 | 171 | 279 | 151 | 61.6 | 240 | 127 | 12.5 | 242 | |||||||||||
Surgery | NO | 98 | 0 | 227.6 | 0.34 | 1536 | 0.10 | 171 | 107 | 235 | 0.03 | 169 | 96 | 242 | 0.62 | 142 | 106 | 178 | 0.80 | ||
YES | 211 | 80.6 | 341.4 | 109 | 0 | 244 | 225 | 188 | 262 | 228 | 0 | 466 | 253 | 30.3 | 476 | ||||||
Nimotuzumab frequency | ≤6 | 89 | 40.5 | 137.5 | 0.27 | 109 | 28.2 | 190 | 0.07 | 171 | 4.11 | 338 | 0.01 | 228 | 72.7 | 383 | 0.85 | . | . | . | 0.06 |
>6 | 211 | 146 | 275.8 | 423 | 83.2 | 763 | 225 | 185 | 265 | 198 | 36.8 | 359 | 253 | 103 | 403 | ||||||
Nimotuzumab doses (mg/w) | ≤200 | 264 | 81.5 | 446.5 | 0.55 | 141 | 0.58 | 163 | 75.5 | 251 | 0.45 | 399 | 85.4 | 713 | 0.30 | . | . | . | 0.06 | ||
>200 | 173 | 40.1 | 305.9 | 423 | 80.4 | 766 | 217 | 174 | 260 | 169 | 105 | 233 | 253 | 103 | 403 |
Bold text indicates statistically significant (P-values <0.05)