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. 2016 Oct 5;6(3):199–206. doi: 10.1016/j.ijpddr.2016.10.001

Table 2.

Frequencies (%) of single nucleotide polymorphism (SNPs) that resulted in an amino acid change at codons E198A (GAA/GCA) and F200Y (TTC/TAC) associated with benzimidazole resistance at isotype-1 β-tubulin gene of Haemonchus contortus from goats and sheep in China.

Populationa P198
 P200
Resistantb Susceptible Resistantc Susceptible
HuB 17 83 4 96
HeB 10 90 2 98
YN 46 54 31 69
SX 0 100 0 100
GX 35 65 25 75
IM 70 30 19 81
LN 40 60 12.5 87.5
HLJ 4 96 8 92
a

HuB-Hubei, HeB-Hebei, YN-Yunnan, SX-Shaanxi, GX-Guangxi, IM-Inner Mongolia, LN-Liaoning, HLJ-Heilongjiang.

b

Resistant = 198A; Susceptible = E198. The allele frequency for 198A was calculated using the data in Table 1 as below: ((Het-198, Hs-200) + (Het-198, Het-200) + 2(HR-198, Hs-200))/2 × 24; The allele frequency for E198 was calculated using the data in Table 1 as below: (2(Hs-198, Hs-200) + (Het-198, Hs-200) + 2(Hs-198, Het-200) + (Het-198, Het-200) + 2(Hs-198, HR-200))/2 × 24.

c

Resistant = 200Y; Susceptible = F200. The allele frequency for 200Y was calculated using the data in Table 1 as follow: ((Hs-198, Het-200) + (Het-198, Het-200) + 2(Hs-198, HR-200))/2 × 24; The allele frequency for F200 was calculated using the data in Table 1 as follow: (2(Hs-198, Hs-200) + 2(Het-198, Hs-200) + (Hs-198, Het-200) + (Het-198, Het-200) + 2(HR-198, Hs-200))/2 × 24.