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Whole-genome messenger RNA profiling and mutational analysis of fresh frozen bladder tumor samples in the TCGA cohort (n = 408). Unsupervised hierarchical clustering was performed with luminal, p53-like, basal, and claudin markers. A. Expression pattern of signature luminal markers. B. Expression pattern of signature basal markers. C. Expression pattern of signature p53 target genes. D. Expression pattern of signature claudin target genes.
