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DJK-5 targeted PSM production. (a) MRSA USA300 PSMα luminescence reporter strain was grown in the presence of 2.5 μg/mL, 5 μg/mL DJK-5 or water as a control. Luminescence activity was read using a VICTORX3 Multilabel Plate reader. (b) PSM production in culture filtrates of S. aureus MRSA USA300 treated with 1 μg/mL of DJK-5 or water as a control. All experiments were done in triplicate and all comparisons were done using unpaired t tests; *, p < 0.05.
