Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Oct 25;10:247. doi: 10.3389/fncel.2016.00247

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Weng, Chen, Wang, Zhuang and Behnisch.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

eEF2K-inhibition mediated-fEPSP potentiation does not rely on protein synthesis. (A) The graph summarizes the mean values of normalized fEPSP slopes for different time points and experimental conditions (control: white circles, n = 4; 5 μM A-484954: black circles, n = 4; 20 μM anisomycin: gray circles, n = 4). (B) Cycloheximide (gray circles, 100 μM, n = 4) did not alter the A-481954-mediated (black circles, n = 4) potentiation of fEPSP. The potentiation of fEPSP remained significantly higher than that observed under control conditions (no A-481954, white circles, n = 4). Horizontal black lines indicate the application period of A-484954 and gray lines indicates the application time of protein synthesis inhibitors. The brackets enclose time points with non-significant (ns) differences between conditions. To the right of the graphs, representative fEPSP traces for the time points 1 and 2 are depicted. Scale bar: 0.5 mV/10 ms.