Table 3. Clinical usefulness of cytology and the HPV DNA genotyping test*.
Variable | HPV DNA chip HR-HPV (+) |
Cytology ≥ASCUS |
---|---|---|
Sensitivity | 86.3 (82.2–89.8) | 94.9 (91.7–97.0) |
Specificity | 60.0 (58.5–61.2) | 41.3 (40.1–42.0) |
Positive predictive value | 43.8 (41.7–45.6) | 36.9 (35.7–37.7) |
Negative predictive value | 92.4 (90.1–94.3) | 95.7 (93.0–97.5) |
Values are presented as percentages (95% CI).
ASCUS, atypical squamous cells of undetermined significance; HPV, human papillomavirus; HR, high-risk.
*HR-HPV (+) includes HPV-16 (+) and/or HPV-18 (+) and/or 12 other non-16/18 HR-HPV (+); ≥ASCUS includes all cytology results that are ASCUS or worse; ≥cervical intraepithelial neoplasia (CIN) 2 includes CIN 2 or worse.