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. 2016 Jul 1;27(6):e56. doi: 10.3802/jgo.2016.27.e56

Table 3. Clinical usefulness of cytology and the HPV DNA genotyping test*.

Variable HPV DNA chip
HR-HPV (+)
Cytology
≥ASCUS
Sensitivity 86.3 (82.2–89.8) 94.9 (91.7–97.0)
Specificity 60.0 (58.5–61.2) 41.3 (40.1–42.0)
Positive predictive value 43.8 (41.7–45.6) 36.9 (35.7–37.7)
Negative predictive value 92.4 (90.1–94.3) 95.7 (93.0–97.5)

Values are presented as percentages (95% CI).

ASCUS, atypical squamous cells of undetermined significance; HPV, human papillomavirus; HR, high-risk.

*HR-HPV (+) includes HPV-16 (+) and/or HPV-18 (+) and/or 12 other non-16/18 HR-HPV (+); ≥ASCUS includes all cytology results that are ASCUS or worse; ≥cervical intraepithelial neoplasia (CIN) 2 includes CIN 2 or worse.