Table 1.
Number of significant spot neighborhoods on the intensity scale for arrays of the experiments analyzed
Microarray | No normalization | Linear normalization | Global lowess | P-lowess | S-lowess | LIN | OLIN | OSLIN |
SW 1 | 596 | 580 | 2 | 5 | 7 | 39 | 12 | 0 |
SW 2 | 1,090 | 1,080 | 0 | 0 | 0 | 52 | 0 | 0 |
SW 3 | 1138 | 988 | 0 | 0 | 0 | 0 | 0 | 0 |
SW 4 | 745 | 655 | 0 | 9 | 4 | 0 | 12 | 0 |
Apo 1 | 1,748 | 1,810 | 18 | 0 | 0 | 26 | 0 | 0 |
Apo 2 | 2,739 | 2,683 | 16 | 17 | 26 | 24 | 0 | 0 |
Apo 3 | 3,479 | 3,559 | 52 | 30 | 15 | 0 | 1 | 0 |
Apo 4 | 2,122 | 2,184 | 1 | 17 | 22 | 0 | 0 | 11 |
Apo 5 | 3,885 | 3,886 | 100 | 13 | 11 | 94 | 0 | 0 |
Apo 6 | 3,540 | 3,555 | 0 | 0 | 0 | 114 | 0 | 0 |
Apo 7 | 3,725 | 3,724 | 0 | 0 | 7 | 0 | 0 | 0 |
Apo 8 | 3,253 | 3,296 | 66 | 0 | 0 | 507 | 0 | 0 |
Apo 9 | 1,040 | 1,044 | 114 | 0 | 0 | 455 | 0 | 0 |
Apo 10 | 1,554 | 1,575 | 0 | 0 | 0 | 45 | 0 | 0 |
Apo 11 | 2,903 | 2,889 | 5 | 34 | 35 | 2 | 0 | 0 |
Apo 12 | 3,536 | 3,543 | 14 | 0 | 0 | 47 | 0 | 0 |
Apo 13 | 2,819 | 2,901 | 132 | 12 | 3 | 354 | 4 | 0 |
Apo 14 | 2,291 | 2,342 | 313 | 0 | 12 | 484 | 64 | 4 |
Apo 15 | 3,050 | 3,034 | 95 | 36 | 0 | 164 | 0 | 0 |
Apo 16 | 1,338 | 1,374 | 159 | 0 | 12 | 918 | 0 | 0 |
Spot neighborhoods are found significant if the median log ratio M has larger positive and negative value than expected from random order of spots along the intensity scale. The level of significance was defined by FDR = 0.01. The spot neighborhood was defined by a symmetrical window of 50 spots.